OR2A12 explained
Olfactory receptor 2A12 is a protein that in humans is encoded by the OR2A12 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
See also
Further reading
- Fuchs T, Malecova B, Linhart C, etal . DEFOG: a practical scheme for deciphering families of genes. . Genomics . 80 . 3 . 295–302 . 2003 . 12213199 . 10.1006/geno.2002.6830 . 10.1.1.145.6233 .
- Gilad Y, Lancet D . Population differences in the human functional olfactory repertoire. . Mol. Biol. Evol. . 20 . 3 . 307–14 . 2003 . 12644552 . 10.1093/molbev/msg013 . free .
- Scherer SW, Cheung J, MacDonald JR, etal . Human chromosome 7: DNA sequence and biology. . Science . 300 . 5620 . 767–72 . 2003 . 12690205 . 2882961 . 10.1126/science.1083423 . 2003Sci...300..767S .
- Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–9 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .
Notes and References
- Web site: Entrez Gene: OR2A12 olfactory receptor, family 2, subfamily A, member 12.
