OR1F1 explained
Olfactory receptor 1F1 is a protein that in humans is encoded by the OR1F1 gene.[1] [2] [3]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
See also
Further reading
- Bernot A . A transcriptional Map of the FMF region . Genomics . 50 . 2 . 147–60 . 1998 . 9653642 . 10.1006/geno.1998.5313 . vanc. Heilig R . Clepet C . 3 . Smaoui . Nizar . Silva . Corinne Da . Petit . Jean-Louis . Devaud . Catherine . Chiannilkulchai . Nuchanard . Fizames . Cécile .
- Fuchs T . DEFOG: a practical scheme for deciphering families of genes . Genomics . 80 . 3 . 295–302 . 2003 . 12213199 . 10.1006/geno.2002.6830 . vanc. Malecova B . Linhart C . 3 . Sharan . Roded . Khen . Miriam . Herwig . Ralf . Shmulevich . Dmitry . Elkon . Rani . Steinfath . Matthias . 10.1.1.135.3652 .
- Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . vanc. Feingold EA . Grouse LH . 3 . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
- Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–9 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .
- Gerhard DS . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . vanc. Wagner L . Feingold EA . 3 . Shenmen . CM . Grouse . LH . Schuler . G . Klein . SL . Old . S . Rasooly . R .
Notes and References
- A candidate gene for familial Mediterranean fever . Nat Genet . 17 . 1 . 25–31 . Oct 1997 . 9288094 . 10.1038/ng0997-25 . French Fmf . Consortium . 24259548 .
- Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D . Distribution of olfactory receptor genes in the human genome . Nat Genet . 18 . 3 . 243–50 . Mar 1998 . 9500546 . 10.1038/ng0398-243 . 31129045 .
- Web site: Entrez Gene: OR1F1 olfactory receptor, family 1, subfamily F, member 1.