OR1E2 explained

Olfactory receptor 1E2 is a protein that in humans is encoded by the OR1E2 gene.^{[1] [2] [3]}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Gotschlich EC . Development of polysaccharide vaccines for the prevention of meningococcal diseases . Monographs in Allergy . 9 . 245–58 . 1975 . 804088 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–9 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Fuchs T, Malecova B, Linhart C, etal . DEFOG: a practical scheme for deciphering families of genes . Genomics . 80 . 3 . 295–302 . 2003 . 12213199 . 10.1006/geno.2002.6830 . 10.1.1.135.3652 .
• Glusman G, Sosinsky A, Ben-Asher E, etal . Sequence, structure, and evolution of a complete human olfactory receptor gene cluster . Genomics . 63 . 2 . 227–45 . 2000 . 10673334 . 10.1006/geno.1999.6030 . 23416814 .

Notes and References

1. Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K, Sheer D, Lehrach H. Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire . Hum Mol Genet . 3 . 2 . 229–35 . Jul 1994 . 8004088 . 10.1093/hmg/3.2.229 . etal.
2. Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D . Distribution of olfactory receptor genes in the human genome . Nat Genet . 18 . 3 . 243–50 . Mar 1998 . 9500546 . 10.1038/ng0398-243 . 31129045 .
3. Web site: Entrez Gene: OR1E2 olfactory receptor, family 1, subfamily E, member 2.