OR1E1 explained

Olfactory receptor 1E1 is a protein that in humans is encoded by the OR1E1 gene.^{[1] [2] [3]}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Rouquier S, Taviaux S, Trask BJ, etal . Distribution of olfactory receptor genes in the human genome . Nat. Genet. . 18 . 3 . 243–50 . 1998 . 9500546 . 10.1038/ng0398-243 . 31129045 .
• Glusman G, Sosinsky A, Ben-Asher E, etal . Sequence, structure, and evolution of a complete human olfactory receptor gene cluster . Genomics . 63 . 2 . 227–45 . 2000 . 10673334 . 10.1006/geno.1999.6030 . 23416814 .
• Rouquier S, Blancher A, Giorgi D . The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates . Proc. Natl. Acad. Sci. U.S.A. . 97 . 6 . 2870–4 . 2000 . 10706615 . 10.1073/pnas.040580197 . 16022 . 2000PNAS...97.2870R . free .
• Fuchs T, Malecova B, Linhart C, etal . DEFOG: a practical scheme for deciphering families of genes . Genomics . 80 . 3 . 295–302 . 2003 . 12213199 . 10.1006/geno.2002.6830 .
• Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–9 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .

Notes and References

1. Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K, Sheer D, Lehrach H. Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire . Hum Mol Genet . 3 . 2 . 229–35 . Jul 1994 . 8004088 . 10.1093/hmg/3.2.229 . etal.
2. Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J. Expression of members of the putative olfactory receptor gene family in mammalian germ cells . Nature . 355 . 6359 . 453–5 . Mar 1992 . 1370859 . 10.1038/355453a0 . 1992Natur.355..453P . 43926 . etal.
3. Web site: Entrez Gene: OR1E1 olfactory receptor, family 1, subfamily E, member 1.