OR13H1 explained

Olfactory receptor 13H1 is a protein that in humans is encoded by the OR13H1 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Parmentier M, Libert F, Schurmans S, etal . Expression of members of the putative olfactory receptor gene family in mammalian germ cells . Nature . 355 . 6359 . 453–5 . 1992 . 1370859 . 10.1038/355453a0 . 1992Natur.355..453P . 43926 .
• Buck L, Axel R . A novel multigene family may encode odorant receptors: a molecular basis for odor recognition . Cell . 65 . 1 . 175–87 . 1991 . 1840504 . 10.1016/0092-8674(91)90418-X . free .
• Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M . Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome . Biochem. Biophys. Res. Commun. . 237 . 2 . 283–7 . 1997 . 9268701 . 10.1006/bbrc.1997.7043 .
• Fuchs T, Malecova B, Linhart C, etal . DEFOG: a practical scheme for deciphering families of genes . Genomics . 80 . 3 . 295–302 . 2003 . 12213199 . 10.1006/geno.2002.6830 .
• Gilad Y, Bustamante CD, Lancet D, Pääbo S . Natural Selection on the Olfactory Receptor Gene Family in Humans and Chimpanzees . Am. J. Hum. Genet. . 73 . 3 . 489–501 . 2003 . 12908129 . 10.1086/378132 . 1180675 .
• Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–9 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .
• Ross MT, Grafham DV, Coffey AJ, etal . The DNA sequence of the human X chromosome . Nature . 434 . 7031 . 325–37 . 2005 . 15772651 . 10.1038/nature03440 . 2665286 . 2005Natur.434..325R .

Notes and References

1. Web site: Entrez Gene: OR13H1 olfactory receptor, family 13, subfamily H, member 1.