OR10A5 explained

Olfactory receptor 10A5 (OR10A5) is a protein that in humans is encoded by the OR10A5 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[2]

See also

• Olfactory receptor

Further reading

• Buettner JA, Glusman G, Ben-Arie N, etal . Organization and evolution of olfactory receptor genes on human chromosome 11. . Genomics . 53 . 1 . 56–68 . 1998 . 9787077 . 10.1006/geno.1998.5422 .
• Lane RP, Cutforth T, Young J, etal . Genomic analysis of orthologous mouse and human olfactory receptor loci. . Proc. Natl. Acad. Sci. U.S.A. . 98 . 13 . 7390–5 . 2001 . 11416212 . 10.1073/pnas.131215398 . 34679 . 2001PNAS...98.7390L . free .
• Gaudin JC, Breuils L, Haertlé T . New GPCRs from a human lingual cDNA library. . Chem. Senses . 26 . 9 . 1157–66 . 2002 . 11705801 . 10.1093/chemse/26.9.1157 .
• Fuchs T, Malecova B, Linhart C, etal . DEFOG: a practical scheme for deciphering families of genes. . Genomics . 80 . 3 . 295–302 . 2003 . 12213199 . 10.1006/geno.2002.6830 . 10.1.1.135.3652 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–9 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .

Notes and References

1. Web site: Entrez Gene: OR10A5 olfactory receptor, family 10, subfamily A, member 5.
2. Web site: Entrez Gene: OR10A5 olfactory receptor, family 10, subfamily A, member 5.