OPN1MW explained

Green-sensitive opsin is a protein that in humans is encoded by the OPN1MW gene.^[1] OPN1MW2 is a similar opsin.

See also

• Opsin

Further reading

• Applebury ML, Hargrave PA . Molecular biology of the visual pigments . Vision Res. . 26 . 12 . 1881–95 . 1987 . 3303660 . 10.1016/0042-6989(86)90115-X . 34038855 .
• Winderickx J, Sanocki E, Lindsey DT, etal . Defective colour vision associated with a missense mutation in the human green visual pigment gene . Nat. Genet. . 1 . 4 . 251–6 . 1993 . 1302020 . 10.1038/ng0792-251 . 23127406 .
• Neitz J, Neitz M, Jacobs GH . Analysis of fusion gene and encoded photopigment of colour-blind humans . Nature . 342 . 6250 . 679–82 . 1990 . 2574415 . 10.1038/342679a0 . 4273929 .
• Nathans J, Thomas D, Hogness DS . Molecular genetics of human color vision: the genes encoding blue, green, and red pigments . Science . 232 . 4747 . 193–202 . 1986 . 2937147 . 10.1126/science.2937147 . 1986Sci...232..193N . 10.1.1.461.5915 .
• Li ZY, Kljavin IJ, Milam AH . Rod photoreceptor neurite sprouting in retinitis pigmentosa . J. Neurosci. . 15 . 8 . 5429–38 . 1995 . 7643192 . 6577619 . 10.1523/JNEUROSCI.15-08-05429.1995.
• Ladekjaer-Mikkelsen AS, Rosenberg T, Jørgensen AL . A new mechanism in blue cone monochromatism . Hum. Genet. . 98 . 4 . 403–8 . 1996 . 8792812 . 10.1007/s004390050229 . 11799731 .
• Ferreira PA, Nakayama TA, Pak WL, Travis GH . Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin . Nature . 383 . 6601 . 637–40 . 1996 . 8857542 . 10.1038/383637a0 . 1996Natur.383..637F . 4304490 .
• Vissers PM, Bovee-Geurts PH, Portier MD, etal . Large-scale production and purification of the human green cone pigment: characterization of late photo-intermediates . Biochem. J. . 330 . 3. 1201–8 . 1998 . 9494086 . 10.1042/bj3301201. 1219262 .
• Bernstein SL, Wong P . Regional expression of disease-related genes in human and monkey retina . Mol. Vis. . 4 . 24 . 1998 . 9815288 .
• Hayashi T, Motulsky AG, Deeb SS . Position of a 'green-red' hybrid gene in the visual pigment array determines colour-vision phenotype . Nat. Genet. . 22 . 1 . 90–3 . 1999 . 10319869 . 10.1038/8798 . 1326234 .
• Ueyama H, Kuwayama S, Imai H, etal . Novel missense mutations in red/green opsin genes in congenital color-vision deficiencies . Biochem. Biophys. Res. Commun. . 294 . 2 . 205–9 . 2002 . 12051694 . 10.1016/S0006-291X(02)00458-8 .
• Zhu X, Brown B, Li A, etal . GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina . J. Neurosci. . 23 . 14 . 6152–60 . 2003 . 12853434 . 6740345 . 10.1523/JNEUROSCI.23-14-06152.2003.
• Bonilha VL, Hollyfield JG, Grover S, Fishman GA . Abnormal distribution of red/green cone opsins in a patient with an autosomal dominant cone dystrophy . Ophthalmic Genet. . 26 . 2 . 69–76 . 2005 . 16020309 . 10.1080/13816810590968041 . 24486298 .

External links

• GeneReviews/NIH/NCBI/UW entry on Red-Green Color Vision Defects

Notes and References

1. Web site: Entrez Gene: OPN1MW opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan).