OMG (gene) explained

Oligodendrocyte-myelin glycoprotein is a protein that in humans is encoded by the OMG gene.^{[1] [2] [3]}

Further reading

• Mikol DD, Gulcher JR, Stefansson K . The oligodendrocyte-myelin glycoprotein belongs to a distinct family of proteins and contains the HNK-1 carbohydrate. . J. Cell Biol. . 110 . 2 . 471–9 . 1990 . 1688857 . 10.1083/jcb.110.2.471 . 2116011 .
• Mikol DD, Stefansson K . A phosphatidylinositol-linked peanut agglutinin-binding glycoprotein in central nervous system myelin and on oligodendrocytes. . J. Cell Biol. . 106 . 4 . 1273–9 . 1988 . 3283151 . 10.1083/jcb.106.4.1273 . 2115011 .
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Mikol DD, Rongnoparut P, Allwardt BA, etal . The oligodendrocyte-myelin glycoprotein of mouse: primary structure and gene structure . Genomics . 17 . 3 . 604–10 . 1993 . 8244377 . 10.1006/geno.1993.1379 .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Wang KC, Koprivica V, Kim JA, etal . Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth . Nature . 417 . 6892 . 941–4 . 2002 . 12068310 . 10.1038/nature00867 . 5734715 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Vourc'h P, Moreau T, Arbion F, etal . Oligodendrocyte myelin glycoprotein growth inhibition function requires its conserved leucine-rich repeat domain, not its glycosylphosphatidyl-inositol anchor . J. Neurochem. . 85 . 4 . 889–97 . 2003 . 12716421 . 10.1046/j.1471-4159.2003.01764.x . 30250786 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Venturin M, Moncini S, Villa V, etal . Mutations and novel polymorphisms in coding regions and UTRs of CDK5R1 and OMG genes in patients with non-syndromic mental retardation . Neurogenetics . 7 . 1 . 59–66 . 2007 . 16425041 . 10.1007/s10048-005-0026-9 . 2434/10108 . 24738309 . free .
• Douglas J, Cilliers D, Coleman K, etal . Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth . Nat. Genet. . 39 . 8 . 963–5 . 2007 . 17632510 . 10.1038/ng2083 . 35797973 .

Notes and References

1. Viskochil D, Cawthon R, O'Connell P, Xu GF, Stevens J, Culver M, Carey J, White R . The gene encoding the oligodendrocyte-myelin glycoprotein is embedded within the neurofibromatosis type 1 gene . Mol Cell Biol . 11 . 2 . 906–12 . Mar 1991 . 1899288 . 359746 . 10.1128/mcb.11.2.906.
2. Mikol DD, Alexakos MJ, Bayley CA, Lemons RS, Le Beau MM, Stefansson K . Structure and chromosomal localization of the gene for the oligodendrocyte-myelin glycoprotein . J Cell Biol . 111 . 6 Pt 1 . 2673–9 . Mar 1991 . 2277079 . 2116377 . 10.1083/jcb.111.6.2673 .
3. Web site: Entrez Gene: OMG oligodendrocyte myelin glycoprotein.