Olfactomedin 3 Explained

Olfactomedin 3, also known as noelin 3 or optimedin, is a protein that in humans is encoded by the OLFM3 gene.^{[1] [2] [3]}

Interactions

OLFM3 has been shown to interact with MYOC.

Further reading

• Kimura K, Wakamatsu A, Suzuki Y, etal . Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes . Genome Res. . 16 . 1 . 55–65 . 2006 . 16344560 . 10.1101/gr.4039406 . 1356129 .
• Rual JF, Venkatesan K, Hao T, etal . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Clark HF, Gurney AL, Abaya E, etal . The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment . Genome Res. . 13 . 10 . 2265–70 . 2003 . 12975309 . 10.1101/gr.1293003 . 403697 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .

Notes and References

1. Torrado M, Trivedi R, Zinovieva R, Karavanova I, Tomarev SI . Optimedin: a novel olfactomedin-related protein that interacts with myocilin . Hum Mol Genet . 11 . 11 . 1291–301 . May 2002 . 12019210 . 10.1093/hmg/11.11.1291 . free .
2. Grinchuk O, Kozmik Z, Wu X, Tomarev S . The Optimedin gene is a downstream target of Pax6 . J Biol Chem . 280 . 42 . 35228–37 . Oct 2005 . 16115881 . 10.1074/jbc.M506195200 . free .
3. Web site: Entrez Gene: OLFM3 olfactomedin 3.