O-acetylhomoserine aminocarboxypropyltransferase explained
| O-acetylhomoserine aminocarboxypropyltransferase |
| Ec Number: | 2.5.1.49 |
| Cas Number: | 37290-90-7 |
| Go Code: | 0003961 |
In enzymology, an O-acetylhomoserine aminocarboxypropyltransferase is an enzyme that catalyzes the chemical reaction
O-acetyl-L-homoserine + methanethiol
L-methionine + acetate
Thus, the two substrates of this enzyme are O-acetyl-L-homoserine and methanethiol, whereas its two products are L-methyionine and acetate.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase. Other names in common use include O-acetyl-L-homoserine acetate-lyase (adding methanethiol), O-acetyl-L-homoserine sulfhydrolase, O-acetylhomoserine (thiol)-lyase, O-acetylhomoserine sulfhydrolase, and methionine synthase. This enzyme participates in methionine metabolism and cysteine metabolism.
References
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- Yamagata S . 1989 . Roles of O-acetyl-L-homoserine sulfhydrylases in micro-organisms . Biochimie . 71 . 1125 - 43 . 2517474 . 11–12 . 10.1016/0300-9084(89)90016-3.
- Kuramitsu S, Iwama T . 2001 . Cloning and overexpression of the oah1 gene encoding O-acetyl-L-homoserine sulfhydrylase of Thermus thermophilus HB8 and characterization of the gene product . Biochim. Biophys. Acta . 1549 . 61 - 72 . 11566369 . 1 . 10.1016/S0167-4838(01)00245-X .
