O-Acetylserine Explained

O-Acetylserine is an α-amino acid with the chemical formula HO2CCH(NH2)CH2OC(O)CH3. It is an intermediate in the biosynthesis of the common amino acid cysteine in bacteria and plants. O-Acetylserine is biosynthesized by acetylation of the serine by the enzyme serine transacetylase. The enzyme O-acetylserine (thiol)-lyase, using sulfide sources, converts this ester into cysteine, releasing acetate:[1]

HO2CCH(NH2)CH2OH → HO2CCH(NH2)CH2OC(O)CH3

HO2CCH(NH2)CH2OC(O)CH3 → HO2CCH(NH2)CH2SH

Notes and References

  1. Hell . R. . Molecular physiology of plant sulfur metabolism . Planta . 202 . 2 . 138–148 . 1997 . 9202491 . 10.1007/s004250050112. 2539629 .

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