| O'Reilly House | |
| Coordinates: | 29.89°N -81.3114°W |
| Mapframe: | yes |
| Mapframe-Marker: | building |
| Mapframe-Zoom: | 12 |
| Mapframe-Caption: | Interactive map showing the location of O'Reilly House |
| Location: | St. Augustine, Florida |
| Added: | October 15, 1974 |
| Refnum: | 74002192 |
The O'Reilly House, known officially known as the Father Miguel O'Reilly House Museum, and also known as the House of Don Lorenzo de Leon, is a historic home in St. Augustine, Florida. It is located at 131 Aviles Street. On October 15, 1974, it was added to the U.S. National Register of Historic Places.
The museum's exhibits focus on the Catholic heritage of St. Augustine.