| Official Name: | Nyaruguru District |
| Settlement Type: | District |
| Subdivision Type: | Country |
| Subdivision Name: | Rwanda |
| Subdivision Type2: | Province |
| Subdivision Name2: | Southern |
| Seat Type: | Capital |
| Seat: | Kibeho |
| Area Total Km2: | 1012 |
| Population As Of: | 2022 census |
| Population Footnotes: | [1] |
| Population Total: | 318126 |
| Population Urban: | 7641 |
| Population Rural: | 310485 |
| Population Density Km2: | auto |
Nyaruguru is a district (akarere) in Southern Province, Rwanda. Its capital is Kibeho, a pilgrimage site of the Catholic Church.
The district is the most southerly in Rwanda, lying between the cities of Butare and Cyangugu and along the Burundian border. It is mountainous, containing part of the montane forest of Nyungwe, one of Rwanda's most popular tourist destinations, which also provides cooking charcoal for much of the Southern region. This is one of the last remaining forest areas of Rwanda and home to chimpanzees and many other species of primate.
Nyaruguru district is divided into 14 sectors (imirenge): Cyahinda, Busanze, Kibeho, Mata, Munini, Kivu, Ngera, Ngoma, Nyabimata, Nyagisozi, Muganza, Ruheru, Ruramba and Rusenge.