| Honorific-Prefix: | His Excellency |
| The Duke of Loulé | |
| Honorific-Suffix: | GCC GCTS FC |
| Monarch1: | Luís I |
| Office1: | President of the Council of Ministers |
| Successor1: | The Duke of Saldanha |
| Term Start1: | 11 August 1869 |
| Term End1: | 19 May 1870 |
| Monarch2: | Pedro V Luís I |
| Predecessor2: | Joaquim António de Aguiar |
| Term Start2: | 4 July 1860 |
| Term End2: | 17 April 1865 |
| Monarch3: | Pedro V |
| Predecessor3: | The Duke of Saldanha |
| Successor3: | The Duke of Terceira |
| Term Start3: | 6 June 1856 |
| Term End3: | 16 March 1859 |
| Birth Date: | 6 November 1804 |
| Birth Place: | Lisbon, Portugal |
| Death Date: | 22 May 1875 (aged 71) |
| Death Place: | Lisbon, Portugal |
| Spouse: | Infanta Ana de Jesus Maria of Portugal |
Dom. Nuno José Severo de Mendoça Rolim de Moura Barreto, 2nd Marquis of Loulé, 9th Count of Vale de Reis, (6 November 1804 – 22 May 1875), was a Portuguese politician during the period of Constitutional Monarchy. He became the 1st Duke of Loulé in 1862.
He was a son of the 1st Marquess of Loule, Agostinho Domingos José de Mendoça Rolim de Moura Barreto. In 1827, he married Infanta Ana de Jesus Maria, younger daughter of King John VI of Portugal. With this marriage, Nuno José Severo become brother-in-law of King Miguel I of Portugal and Emperor Pedro I of Brazil, and paternal uncle of Queen Maria II of Portugal and Emperor Pedro II of Brazil.They had five children:
Leader of the Historic Party, he was many times minister and, for three times, President of the Council of Ministers – Prime Minister (1856–1859, 1860–1865 and 1869–1870).