| Winner: | Artemisa Rivera [1] |
| Represented: | Zacatecas City |
| Date: | July 12, 2012 |
| Acts: | Dan Masciarelli, Kristina Koban |
| Entrants: | 10 |
| Placements: | 3 |
| Venue: | Teatro Ramón López Velarde, Zacatecas, Zacatecas |
| Broadcaster: | Televisa |
Nuestra Belleza Zacatecas 2012, was held at the Teatro Ramón López Velarde of Zacatecas, Zacatecas on July 12, 2012. At the conclusion of the final night of competition Artemisa River from Zacatecas City was crown the winner. Rivera was crowned by Nuestra Belleza Zacatecas titleholder Michelle Román. Ten contestants competed for the title.
| Final Results | Contestant | |
|---|---|---|
| Nuestra Belleza Zacatecas 2012 |
| |
| 1st Runner-up |
| |
| 2nd Runner-up |
|
| Hometown | Contestant | |
|---|---|---|
| Cd. Cuauhtémoc | Roxana Reyes Herrera | |
| Fresnillo | Olivia Noemí Espino Rodríguez | |
| Fresnillo | Itzel Bethzaida Martínez Rucobo Rincón | |
| Guadalupe | Judith Alejandra Martínez Rivera | |
| Jalapa | Edna Denisse Chávez Ruiz | |
| Jerez | Daniela Medina Revele | |
| Juchipila | Elizabeth Cervantes Luján | |
| Teúl de González Ortega | Itzel Uribe Carrillo | |
| Zacatecas | Thalía Artemisa Rivera Montañez | |
| Zacatecas | María Victoria Loya Rico |