Nuestra Belleza Chiapas 2010, was held at the Polyforum Chiapas, Tuxtla Gutiérrez, Chiapas on July 27, 2010. At the conclusion of the final night of competition, Grissel Hernández of Tecpatán was crowned the winner. Hernández was crowned by outgoing Nuestra Belleza Chiapas titleholder, Claudia Espinoza. Twelve contestants competed for the state title.
| Final Results | Contestant | |
|---|---|---|
| Nuestra Belleza Chiapas 2010 |
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| Nuestra Belleza Turismo Chiapas 2011 |
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| Reina de la Feria de Chiapas 2011 |
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| Suplente / 1st Runner-up |
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| 2nd Runner-up |
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| Hometown | Contestant | |
|---|---|---|
| Acapetahua | Esperanza Hilerio | |
| Catazajá | Andrea Coello | |
| Tuxtla Gutierrez | Stephanie Pimentel | |
| Comitán | Zuleyma Nuricumbo | |
| Tuxtla Gutierrez | Irene Quinteros | |
| Palenque | Fernanda Gutiérrez | |
| Cintalapa | Jessica Garcia | |
| Tapachula | Carolina del Río | |
| Tecpatán | Grissel Hernández | |
| Comitán | Karen Lazcano Córdoba | |
| Villa Corzo | Lupita Ruíz | |
| Villaflores | Karla Montesinos |