| NrsZ sRNA | |
| Rfam: | RF02695 |
| Tax Domain: | Bacteria |
NrsZ (nitrogen regulated small RNA) is a bacterial small RNA found in the opportunistic pathogen Pseudomonas aeruginosa PAO1. Its transcription is induced during nitrogen limitation by the NtrB/C two-component system (an important regulator of nitrogen assimilation and swarming motility) together with the alternative sigma factor RpoN (a global regulator involved in nitrogen metabolism). NrsZ by activating rhlA (a gene essential for rhamnolipids synthesis) positively regulates the production of rhamnolipid surfactants needed for swarming motility.[1]