| Official Name: | Novokhrenovoye |
| Native Name: | Новохреновое |
| Native Name Lang: | ru |
| Settlement Type: | Selo |
| Pushpin Map: | Russia Voronezh Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Type1: | Region |
| Subdivision Name1: | Voronezh Oblast |
| Subdivision Type2: | County |
| Subdivision Type3: | District |
| Subdivision Name3: | Paninsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 51.5667°N 94°W[1] |
Novokhrenovoye (Russian: links=no|Новохреновое) is a rural locality (a selo) in Oktyabrskoye Rural Settlement, Paninsky District, Voronezh Oblast, Russia. The population was 489 as of 2010.[2] There are 9 streets.[3]
Novokhrenovoye is located on the right bank of the Tamlyk River, 18 km southwest of Panino (the district's administrative centre) by road. Novokhrenovoye is the nearest rural locality.[4]