| Province: | NS |
| Type: | Trunk |
| Route: | 22 |
| Alternate Name: | Mira Road |
| Length Km: | 35.6 |
| Direction A: | North |
| Terminus A: | in Sydney |
| Junction: | in Sydney |
| Direction B: | South |
| Terminus B: | Louisbourg |
| Municipalities: | Cape Breton Regional Municipality |
| Previous Type: | Trunk |
| Previous Route: | 19 |
| Next Type: | Trunk |
| Next Route: | 28 |
Trunk 22 is part of the Canadian province of Nova Scotia's system of trunk highways. The route runs from Sydney to Louisbourg, a distance of 36km (22miles).
Trunk 22, which leaves Sydney to the southeast on George Street, is known over most of its route as the Mira Road. The route crosses the Mira River at Albert Bridge.[1]