| State: | ND |
| Type: | ND |
| Route: | 45 |
| Length Mi: | 18.048 |
| Length Round: | 3 |
| Established: | c. 1927 |
| Map Custom: | yes |
| Direction A: | South |
| Terminus A: | in Cooperstown |
| Direction B: | North |
| Terminus B: | west of Sharon |
| Counties: | Griggs, Steele |
| Previous Type: | ND |
| Previous Route: | 44 |
| Next Type: | ND |
| Next Route: | 46 |
North Dakota Highway 45 (ND 45) is an 18.048adj=midNaNadj=mid north–south state highway in the U.S. state of North Dakota. ND 45's southern terminus is at ND 200 in Cooperstown, and the northern terminus is at ND 32 west of Sharon.[1]