Norma Andrews Explained

Norma W. Andrews is a cell biologist and professor at the University of Maryland Department of Cell Biology and Molecular Genetics. She chaired the department from 2009 to 2014.^[1]

Education and career

Norma Andrews received her B.S. in 1977 and Ph.D. in 1983, both from the University of São Paulo.^[2] She then went on to a postdoctoral fellowship in the laboratory of Victor Nussenzweig at New York University, which she completed in 1990.^[2] She then began her own laboratory at Yale University, where she joined the Department of Cell Biology and the Section of Microbial Pathogenesis becoming a Full Professor in 1999.^[2] In 2009, Andrews moved her lab to the University of Maryland to chair the Department of Cell Biology and Molecular Genetics.^[1] She stepped down from that position in 2014.^[1]

Research

Andrews' research has focused on the cell biology of mammalian cells and their response to intracellular parasitic eukaryotes such as Trypanosoma cruzi and Leishmania.^[3] Her group is known for discovering and characterizing calcium-dependent exocytosis of lysosomes in mammalian cells, and its role in repair of the plasma membrane.^{[2] [3]}

Notable publications

• Idone V, Tam C... Andrews NW (2008). Repair of injured plasma membrane by rapid Ca²⁺ dependent endocytosis. Journal of Cell Biology. 180(5): pgs. 905-914
• Reddy A, Caler EV, Andrews NW (2001). Plasma membrane repair is mediated by Ca²⁺-regulated exocytosis of lysosomes. Cell. 106(2): pgs. 157-169
• Martinez I, Chakrabarti S... Andrews NW (2000). Synaptotagmin vii regulated Ca²⁺-dependent exocytosis of lysosomes in fibroblasts. Journal of Cell Biology. 148(6): pgs. 1141-1149
• Rodriguez A, Webster P... Andrews NW (1997). Lysosomes behave as Ca²⁺-regulated exocytic vesicles in fibroblasts and epithelial cells. Journal of Cell Biology. 137(1): pgs. 93-104
• Tardieux I, Webster P... Andrews NW (1992). Lysosome recruitment and fusion are early events required for trypanosome invasion of mammalian cells. Cell. 71(7): pgs. 1117-1130
• Tam C, Idone V... Andrews NW (2010). Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair. Journal of Cell Biology. 189(6): pgs. 1027-1038

Notes and References

1. Web site: Current Lab Members . 16 July 2019 . Andrews Lab - University of Maryland.
2. Web site: Norma Andrews . 16 July 2019 . iBiology.
3. Web site: Norma W. Andrews . 16 July 2019 . University of Maryland.