Nomegestrol Explained

Nomegestrol, also known as 19-normegestrol, is a steroidal progestin which was patented in 1975 but was never marketed.^{[1] [2]} It is the parent compound of nomegestrol acetate, which is marketed as a progestin.

Nomegestrol shows relatively low affinity for the progesterone receptor, only about 4% of that of progesterone and about 1.6% of that of nomegestrol acetate in one assay.^[3]

See also

• Medroxyprogesterone
• Megestrol

Notes and References

1. Book: J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. 14 November 2014. Springer. 978-1-4757-2085-3. 883–.
2. Book: Index Nominum 2000: International Drug Directory. January 2000. Taylor & Francis. 978-3-88763-075-1. 747–.
3. Botella J, Duc I, Delansorne R, Paris J, Lahlou B . Structure-activity and structure-affinity relationships of 19-nor-progesterone derivatives in rat uterus . J. Endocrinol. Invest. . 13 . 11 . 905–10 . December 1990 . 2090671 . 10.1007/BF03349652 . 37429648 .