Nojirimycin Explained

Nojirimycin is the parent compound of a class of antibiotics and glycosidase inhibitors. Nojirimycin and its derivatives are mainly obtained from a class of Streptomyces species.^[1] Chemically, it is an iminosugar.

Derivatives

• 1-deoxynojirimycin or duvoglustat
• 1-deoxygalactonojirimycin or migalastat, a drug for the treatment of Fabry disease

Notes and References

1. 10.1016/0040-4020(68)88115-3. 5636917. Structure and synthesis of nojirimycin. Tetrahedron. 24. 5. 2125–44. 1968. Inouye. S.. Tsuruoka. T.. Ito. T.. Niida. T..