| Noche de Sexo | |
| Type: | single |
| Artist: | Wisin & Yandel featuring Romeo Santos |
| Album: | Pa'l Mundo |
| Released: | November 12th, 2005 |
| Recorded: | 2005 |
| Genre: | Reggaeton |
| Length: | 3:25 |
| Prev Title: | Llamé Pa' Verte (Bailando Sexy) |
| Prev Year: | 2005 |
| Next Title: | Pam Pam |
| Next Year: | 2005 |
"Noche de Sexo" (English: "Night of Sex") is a song by Wisin & Yandel, featuring Romeo Santos of Aventura. The single reached number 17 on the Billboard Hot Latin Tracks Year-End Chart of 2005. This was the first collaboration between the two groups. The song was nominated for Hot Latin Songs of the Year by Vocal Duet or Collaboration at the 2005 Latin Billboard Music Awards losing to "La Tortura" by Shakira and Alejandro Sanz.