Niveen Khashab Explained
Niveen M. Khashab is a Lebanese chemist and an associate Professor of chemical Sciences and engineering at King Abdullah University of Science and Technology in Saudi Arabia since 2009.[1] [2] She is a laureate of the 2017 L'Oréal-UNESCO Awards for Women in Science "for her contributions to innovative smart hybrid materials aimed at drug delivery and for developing new techniques to monitor intracellular antioxidant activity."[3] She is also a fellow of the Royal Chemical Society, and a member of the American Chemical Society.[4]
Education
Niveen M. Khashab received her B.S. in Chemistry from the American University of Beirut, Lebanon, followed by her PhD in chemistry at the University of Florida.[5] [6]
Research & Career
Professor Khashab's research focuses on the design, synthesis, and use of "smart" programmable nanomaterials, emphasizing the systems' controlled release and delivery characteristics.[7] [8] [9] These synthetic materials are applied for biomimetic biological (distribution, sensing, and imaging), industrial (nanocomposites), and environmental (synthesis of membranes) applications, respectively.[10] [11] [12] [13] Niveen's research interests include leveraging the natural microporosity of supramolecular assemblies for energy-intensive separations. Her research team is particularly interested in the separation of benzene derivatives employing macrocycles and cages designed for optimal separation via molecular recognition.[14] Her team has produced a variety of self-assembled capsules (SACs) for the encapsulation and transport of RNA, DNA, and proteins. She focuses on the encapsulation and delivery of CRISPR-Cas9 to enhance targeted gene editing.[15] [16]
With more than ten years of professional experience, Prof. Niveen M. Khashab is presently a Full Professor and Head of the Chemistry Program at the King Abdullah University of Science and Technology.
Bibliography
- Carbon Nanomaterials Sourcebook: Graphene, Fullerenes, Nanotubes, and Nanodiamonds, Volume I.[17]
Patents
Prof. Niveen M. Khashab has obtained many patents for her inventions including:
Publications
- Jonas G. Croissant, Yevhen Fatieiev, Niveen M. Khashab. "Degradability and Clearance of Silicon, Organosilica, Silsesquioxane, Silica Mixed Oxide, and Mesoporous Silica Nanoparticles". WIley Online Library.[18]
- Jonas G. Croissant, Yevhen Fatieiev, Abdulaziz Almalik, Niveen M. Khashab. "Mesoporous Silica and Organosilica Nanoparticles: Physical Chemistry, Biosafety, Delivery Strategies, and Biomedical Applications". WIley Online Library.[19]
- Shahad K Alsaiari, Sachin Patil, Mram Alyami, Kholod O Alamoudi, Fajr A Aleisa, Jasmeen S Merzaban, Mo Li, and Niveen M Khashab. "Endosomal Escape and Delivery of CRISPR/Cas9 Genome Editing Machinery Enabled by Nanoscale Zeolitic Imidazolate Framework". ACS Publications.[20]
- Jonas G. Croissant, Xavier Cattoën, Michel Wong Chi Man, Jean-Olivier Durand and Niveen M. Khashab. "Syntheses and applications of periodic mesoporous organosilica nanoparticles". Nanoscale.[21]
- Jonas G Croissant, Dingyuan Zhang, Shahad Alsaiari, Jie Lu, Lin Deng, Fuyuhiko Tamanoi, Abdulaziz M AlMalik, Jeffrey I Zink, and Niveen M Khashab. "Protein-gold clusters-capped mesoporous silica nanoparticles for high drug loading, autonomous gemcitabine/doxorubicin co-delivery, and in-vivo tumor imaging". Journal of Controlled Release.[22]
- Mram Z Alyami, Shahad K Alsaiari, Yanyan Li, Somayah S Qutub, Fajr A Aleisa, Rachid Sougrat, Jasmeen S Merzaban, and Niveen M Khashab. "Cell-Type-Specific CRISPR/Cas9 Delivery by Biomimetic Metal Organic Frameworks". ACS Publications.[23]
Awards
Niveen won the Great Arab Minds Award in Natural Sciences in 2023 for her contributions to chemistry, bioengineering, and biology.[24]
External links
Notes and References
- https://www.kaust.edu.sa/en/study/faculty/niveen-khashab Niveen Khashab's page on King Abdullah University of Science and Technology's website
- Web site: Her CV . 2016-10-13 . https://web.archive.org/web/20161014061652/https://shms.kaust.edu.sa/Documents/Niveen%20CV%20(04-08-2010).pdf . 2016-10-14 . dead .
- http://www.unesco.org/new/en/media-services/single-view/news/announcement_of_laureates_of_2017_loreal_unesco_for_wome/ Announcement of Laureates of 2017 L’Oréal-UNESCO For Women in Science Awards
- Web site: Congratulations to the 2023 Cram Lehn Pedersen Prize Winner: Niveen Khashab – Chemical Communications Blog . 2023-03-03 . en-US.
- Web site: Niveen Khashab . 2023-03-03 . KAUST PORTAL FOR RESEARCHERS AND STUDENTS . en-US.
- Web site: 2019-03-29 . A young researcher in the spotlight: Niveen M. Khashab - ISGS . 2023-03-03 . en-US.
- Web site: International . Drug Patents . 2016-01-03 . One Organic Chemist One Day: Niveen M. Khashab . 2023-03-03 . One Organic Chemist One Day.
- Min Song . Hyon . H. Anjum . Dalaver . M. Khashab . Niveen . 2012 . Shape-controlled synthesis of Au@Pd core-shell nanoparticles and their corresponding electrochemical properties . RSC Advances . en . 2 . 9 . 3621–3624 . 10.1039/C2RA20152F. 2012RSCAd...2.3621S .
- Li . Song . Li . Wengang . Khashab . Niveen M. . 2012-12-01 . Stimuli responsive nanomaterials for controlled release applications . Nanotechnology Reviews . en . 1 . 6 . 493–513 . 10.1515/ntrev-2012-0033 . 135482439 . 2191-9097. free .
- Huang . Guoyou . Li . Fei . Zhao . Xin . Ma . Yufei . Li . Yuhui . Lin . Min . Jin . Guorui . Lu . Tian Jian . Genin . Guy M. . Xu . Feng . 2017-10-25 . Functional and Biomimetic Materials for Engineering of the Three-Dimensional Cell Microenvironment . Chemical Reviews . en . 117 . 20 . 12764–12850 . 10.1021/acs.chemrev.7b00094 . 0009-2665 . 6494624 . 28991456.
- Chand . Santanu . Alahmed . Othman . Baslyman . Walaa S. . Dey . Avishek . Qutub . Somayah . Saha . Ranajit . Hijikata . Yuh . Alaamery . Manal . Khashab . Niveen M. . 2022-03-28 . DNA-Mimicking Metal–Organic Frameworks with Accessible Adenine Faces for Complementary Base Pairing . JACS Au . en . 2 . 3 . 623–630 . 10.1021/jacsau.1c00516 . 2691-3704 . 8969998 . 35373199.
- Alimi . Lukman O. . Fang . Fang . Moosa . Basem . Ding . Yanjun . Khashab . Niveen M. . 2022-10-24 . Vapor‐Triggered Mechanical Actuation in Polymer Composite Films Based on Crystalline Organic Cages . Angewandte Chemie International Edition . en . 61 . 43 . e202212596 . 10.1002/anie.202212596 . 36047488 . 251978883 . 1433-7851. free . 10754/680836 . free .
- Huang . Tiefan . Moosa . Basem A. . Hoang . Phuong . Liu . Jiangtao . Chisca . Stefan . Zhang . Gengwu . AlYami . Mram . Khashab . Niveen M. . Nunes . Suzana P. . 2020-11-18 . Molecularly-porous ultrathin membranes for highly selective organic solvent nanofiltration . Nature Communications . en . 11 . 1 . 5882 . 10.1038/s41467-020-19404-6 . 33208753 . 7674481 . 2020NatCo..11.5882H . 2041-1723.
- Zhang . Gengwu . Hua . Bin . Dey . Avishek . Ghosh . Munmun . Moosa . Basem A. . Khashab . Niveen M. . 2021-01-05 . Intrinsically Porous Molecular Materials (IPMs) for Natural Gas and Benzene Derivatives Separations . Accounts of Chemical Research . en . 54 . 1 . 155–168 . 10.1021/acs.accounts.0c00582 . 33332097 . 229316181 . 0001-4842.
- O. Alimi . Lukman . Z. Alyami . Mram . Chand . Santanu . Baslyman . Walaa . M. Khashab . Niveen . 2021 . Coordination-based self-assembled capsules (SACs) for protein, CRISPR–Cas9, DNA and RNA delivery . Chemical Science . en . 12 . 7 . 2329–2344 . 10.1039/D0SC05975G. 34163998 . 8179292 .
- Alsaiari . Shahad K . Patil . Sachin . Alyami . Mram . Alamoudi . Kholod O . Aleisa . Fajr A . Merzaban . Jasmeen S . Li . Mo . Khashab . Niveen M . 2018-01-01 . Endosomal Escape and Delivery of CRISPR/Cas9 Genome Editing Machinery Enabled by Nanoscale Zeolitic Imidazolate Framework . Journal of the American Chemical Society . 140 . 1 . 143–146 . 10.1021/jacs.7b11754 . 1520-5126 . 29272114. 10754/626437 . free .
- Book: Carbon nanomaterials sourcebook. Volume 1, Graphene, fullerenes, nanotubes, and nanodiamonds . 2016 . Klaus D. Sattler . 978-1-4822-5269-9 . Boca Raton, FL . 945552732.
- Croissant . Jonas G. . Fatieiev . Yevhen . Khashab . Niveen M. . March 2017 . Degradability and Clearance of Silicon, Organosilica, Silsesquioxane, Silica Mixed Oxide, and Mesoporous Silica Nanoparticles . Advanced Materials . en . 29 . 9 . 1604634 . 10.1002/adma.201604634. 28084658 . 2017AdM....2904634C . 205274162 .
- Croissant . Jonas G. . Fatieiev . Yevhen . Almalik . Abdulaziz . Khashab . Niveen M. . February 2018 . Mesoporous Silica and Organosilica Nanoparticles: Physical Chemistry, Biosafety, Delivery Strategies, and Biomedical Applications . Advanced Healthcare Materials . en . 7 . 4 . 1700831 . 10.1002/adhm.201700831. 29193848 . 3445633 . 10754/626577 . free .
- Alsaiari . Shahad K. . Patil . Sachin . Alyami . Mram . Alamoudi . Kholod O. . Aleisa . Fajr A. . Merzaban . Jasmeen S. . Li . Mo . Khashab . Niveen M. . 2018-01-10 . Endosomal Escape and Delivery of CRISPR/Cas9 Genome Editing Machinery Enabled by Nanoscale Zeolitic Imidazolate Framework . Journal of the American Chemical Society . en . 140 . 1 . 143–146 . 10.1021/jacs.7b11754 . 29272114 . 10754/626437 . 0002-7863. free .
- Croissant . Jonas G. . Cattoën . Xavier . Man . Michel Wong Chi . Durand . Jean-Olivier . Khashab . Niveen M. . 2015-12-03 . Syntheses and applications of periodic mesoporous organosilica nanoparticles . Nanoscale . en . 7 . 48 . 20318–20334 . 10.1039/C5NR05649G . 26585498 . 2015Nanos...720318C . 2040-3372.
- Croissant . Jonas G. . Zhang . Dingyuan . Alsaiari . Shahad . Lu . Jie . Deng . Lin . Tamanoi . Fuyuhiko . AlMalik . Abdulaziz M. . Zink . Jeffrey I. . Khashab . Niveen M. . 2016-05-10 . Protein-gold clusters-capped mesoporous silica nanoparticles for high drug loading, autonomous gemcitabine/doxorubicin co-delivery, and in-vivo tumor imaging . Journal of Controlled Release . en . 229 . 183–191 . 10.1016/j.jconrel.2016.03.030 . 27016140 . 10754/603622 . 0168-3659. free .
- Alyami . Mram Z. . Alsaiari . Shahad K. . Li . Yanyan . Qutub . Somayah S. . Aleisa . Fajr A. . Sougrat . Rachid . Merzaban . Jasmeen S. . Khashab . Niveen M. . 2020-01-29 . Cell-Type-Specific CRISPR/Cas9 Delivery by Biomimetic Metal Organic Frameworks . Journal of the American Chemical Society . en . 142 . 4 . 1715–1720 . 10.1021/jacs.9b11638 . 31931564 . 10754/678579 . 210194377 . 0002-7863. free .
- Web site: Lebanese Prof. Niveen Khashab Wins Great Arab Minds Award in Natural Sciences . 2024-07-31 . english.aawsat.com . en.