Nitrate reductase (NADH) explained

Nitrate reductase (NADH)
Ec Number:	1.7.1.1
Cas Number:	9013-03-0

Nitrate reductase (NADH) (assimilatory nitrate reductase, NADH-nitrate reductase, NADH-dependent nitrate reductase, assimilatory NADH: nitrate reductase, nitrate reductase (NADH₂), NADH₂: nitrate oxidoreductase) is an enzyme with systematic name nitrite: NAD⁺ oxidoreductase.^{[1] [2] [3] [4] [5]} This enzyme catalyzes the following chemical reaction

nitrite + NAD⁺ + H₂O

\rightleftharpoons nitrate + NADH + H⁺

Nitrate reductase is an iron-sulfur molybdenum flavoprotein.

Notes and References

1. Fewson CA, Nicholas DJ . Nitrate reductase from Pseudomonas aeruginosa . Biochimica et Biophysica Acta . 49 . 335–49 . May 1961 . 2 . 13699254 . 10.1016/0006-3002(61)90133-0 .
2. Book: Nitrate reductases . The Enzymes . Nason A . 1963 . 7 . 587–607 . Boyer PD, Lardy H, Myrbäck K . 2nd . Academic Press . New York .
3. Nicholas DJ, Nason A . Diphosphopyridine nucleotide-nitrate reductase from Escherichia coli . Journal of Bacteriology . 69 . 5 . 580–3 . May 1955 . 10.1128/JB.69.5.580-583.1955 . 14381380 . 357589.
4. A reduced diphosphopyridine-specific nitrate reductase from germinating wheat . Spencer D . Aust. J. Biol. Sci. . 1959 . 12 . 181–189 . 10.1071/bi9590181.
5. Berks BC, Ferguson SJ, Moir JW, Richardson DJ . Enzymes and associated electron transport systems that catalyse the respiratory reduction of nitrogen oxides and oxyanions . Biochimica et Biophysica Acta (BBA) - Bioenergetics . 1232 . 3 . 97–173 . December 1995 . 8534676 . 10.1016/0005-2728(95)00092-5 . free .