Nitemazepam Explained

Nitemazepam (or 3-hydroxynimetazepam) is a benzodiazepine derivative which was first synthesised in the 1970s but was never marketed. It is the 7-nitro instead of 7-chloro analogue of temazepam, and also the 3-hydroxy derivative of nimetazepam, and an active metabolite. It has in more recent years been sold as a designer drug, first being definitively identified in Europe in 2017. It is metabolized to 7-aminonitemazepam, nimetazepam, 3-hydroxynitemazepam, temazepam, and nimetazepam glucuronide.^{[1] [2]}

Notes and References

1. Zawilska JB, Wojcieszak J . An expanding world of new psychoactive substances-designer benzodiazepines . Neurotoxicology . 73 . 8–16 . July 2019 . 30802466 . 10.1016/j.neuro.2019.02.015 . 73461430 .
2. Book: Moosmann B, Auwärter V . 2018 . Designer Benzodiazepines: Another Class of New Psychoactive Substances. . Maurer H, Brandt S . New Psychoactive Substances . Handbook of Experimental Pharmacology . 252 . 383–410 . 10.1007/164_2018_154 . 30367253 . 978-3-030-10560-0 .