| Official Name: | Nipissing District |
| Other Name: | District de Nipissing |
| Settlement Type: | District |
| Coordinates: | 46.3°N -79.45°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Canada |
| Subdivision Type1: | Province |
| Subdivision Type2: | Region |
| Subdivision Name2: | Northeastern Ontario |
| Established Title: | Created |
| Established Date: | 1858 |
| Leader Title: | MPs |
| Leader Name: | Anthony Rota, Cheryl Gallant, Marc Serré |
| Leader Title1: | MPPs |
| Leader Name1: | Vic Fedeli, John Vanthof, John Yakabuski |
| Area Land Km2: | 17103.52 |
| Population Total: | 84716 |
| Population As Of: | 2021 |
| Population Density Km2: | 5 |
| Postal Code Type: | Postal code FSA |
| Postal Code: | P0A, P0B, P1A-P1C, P2B |
| Area Code: | 705 |
| Timezone: | Eastern (EST) |
| Utc Offset: | -5 |
| Timezone Dst: | EDT |
| Utc Offset Dst: | -4 |
| Blank Name: | Seat |
| Blank Info: | North Bay |
Nipissing District is a district in Northeastern Ontario in the Canadian province of Ontario. It was created in 1858. The district seat is North Bay.
In 2016, the population was 83,150. The land area is ; the population density was, making it one of the most densely populated districts in northern Ontario.
The Sudbury District was created in 1894 from townships of eastern Algoma District and west Nipissing District. The Timiskaming District was created in 1912 from parts of Algoma, Nipissing, and Sudbury Districts.
In addition, the eastern part of the town of Kearney is within Nipissing District, but the entire town is enumerated with the Parry Sound District.
Local services boards in these unorganized areas include:
As a census division in the 2021 Census of Population conducted by Statistics Canada, the Nipissing District had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of 16986.2km2, it had a population density of in 2021.[1]