Ninein-like protein explained

Ninein-like protein is a protein that in humans is encoded by the NINL gene.^{[1] [2]} It is part of the centrosome.^[3]

Further reading

• Wang Y, Zhan Q . Cell cycle-dependent expression of centrosomal ninein-like protein in human cells is regulated by the anaphase-promoting complex. . J. Biol. Chem. . 282 . 24 . 17712–9 . 2007 . 17403670 . 10.1074/jbc.M701350200 . free.
• Casenghi M, Barr FA, Nigg EA . Phosphorylation of Nlp by Plk1 negatively regulates its dynein-dynactin-dependent targeting to the centrosome. . J. Cell Sci. . 118 . Pt 21 . 5101–8 . 2005 . 16254247 . 10.1242/jcs.02622 . 23146359 .
• Rual JF, Venkatesan K, Hao T, etal . Towards a proteome-scale map of the human protein-protein interaction network. . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Casenghi M, Meraldi P, Weinhart U, etal . Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation. . Dev. Cell . 5 . 1 . 113–25 . 2003 . 12852856 . 10.1016/S1534-5807(03)00193-X . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Deloukas P, Matthews LH, Ashurst J, etal . The DNA sequence and comparative analysis of human chromosome 20. . Nature . 414 . 6866 . 865–71 . 2002 . 11780052 . 10.1038/414865a . 2001Natur.414..865D . free .

Notes and References

1. Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O . Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro . DNA Res . 6 . 1 . 63–70 . Jul 1999 . 10231032 . 10.1093/dnares/6.1.63 . free .
2. Web site: Entrez Gene: RP4-691N24.1 KIAA0980 protein.
3. Ph.D . Functional characterization of the novel centrosomal protein Nlp (ninein-like protein) . Casenghi . Martina . 2003 .