| Official Name: | Nikolskoye |
| Native Name: | Никольское |
| Settlement Type: | Selo |
| Pushpin Map: | Russia Vologda Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Vologda Oblast |
| Subdivision Name3: | Ust-Kubinsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 59.8333°N 61°W[1] |
Nikolskoye (Russian: Никольское) is a rural locality (a selo) and the administrative center of Nikolskoye Rural Settlement, Ust-Kubinsky District, Vologda Oblast, Russia. The population was 451 as of 2002.[2] There are 8 streets.[3]
From 1885 to 1933, the local hospital was run by the Belarusian physician Nadezhda Bantle, who according to locals reformed it into the most advanced hospital in the region.[4]
The distance to Ustye is 33 km. Filenskoye is the nearest rural locality.