| Nikolai Agafonov | |
| Fullname: | Nikolai Vasilyevich Agafonov |
| Birth Date: | 15 June 1947 |
| Position: | Midfielder |
| Years1: | 1965–1970 |
| Years2: | 1971–1974 |
| Manageryears1: | 1982–1987 |
| Manageryears2: | 1987–1991 |
| Managerclubs2: | FC Uralmash Sverdlovsk (assistant) |
| Manageryears3: | 1991–1992 |
| Manageryears4: | 1998–2001 |
| Managerclubs4: | FC Uralmash Yekaterinburg |
| Manageryears5: | 2002 |
| Managerclubs5: | FC Kuzbass-Dynamo Kemerovo |
Nikolai Vasilyevich Agafonov (Russian: Николай Васильевич Агафонов; born 15 June 1947) is a Russian professional football coach and a former player.