Nicotine polacrilex explained
Drug Name: | Nicotine polacrilex |
Width: | 250px |
Tradename: | Nicorette |
Dailymedid: | Nicotine polacrilex |
Routes Of Administration: | By mouth |
Atc Prefix: | None |
Legal Uk: | GSL |
Legal Uk Comment: | [1] [2] |
Legal Us: | OTC |
Legal Us Comment: | [3] |
Unii: | 6M3C89ZY6R |
Nicotine polacrilex is nicotine bound to an ion-exchange resin (polymethacrylic acid, such as Amberlite IRP64, Purolite C115HMR or Doshion P551).[4] It is added to gum and hard lozenges used for nicotine replacement therapy in smoking cessation, such as in the Nicorette range of products. The use of the polymer as a delivery system maximizes the amount of nicotine released and absorbed by the oral mucosa. 80 to 90 percent of the nicotine released from the gum is absorbed by the mouth. Side effects of the gum include bad taste, nausea, dyspepsia, and stomatitis.
Notes and References
- Web site: Nicorette 2mg Gum Summary of Product Characteristics (SmPC) . emc . 1 September 2021 . 17 July 2024.
- Web site: Nicorette 4mg Gum Summary of Product Characteristics (SmPC) . emc . 1 September 2021 . 17 July 2024.
- Web site: Nicorette White Ice Mint- nicotine polacrilex gum, chewing Nicorette Original- nicotine polacrilex gum, chewing Nicorette Cinnamon Surge- nicotine polacrilex gum, chewing Nicorette Fresh Mint- nicotine polacrilex gum, chewing Nicorette Mint- nicotine polacrilex gum, chewing Nicorette Spearmint Burst- nicotine polacrilex gum, chewing . DailyMed . 11 November 2021.
- Web site: Nicotine polacrilex . U.S. National Library of Medicine . Drug Information Portal . 2021-11-12 . 2021-11-12 . https://web.archive.org/web/20211112015632/https://druginfo.nlm.nih.gov/drugportal/rn/96055-45-7 . live .