| Nicola Lo Buono | |
| Fullname: | Nicola Lo Buono |
| Birth Date: | 4 June 1933 |
| Birth Place: | Bari, Italy |
| Death Date: | 8 September 2009 |
| Position: | Defender |
| Years1: | 1954 - 1955 |
| Clubs1: | Fortis Trani |
| Caps1: | ? |
| Goals1: | ? |
| Years2: | 1955 - 1961 |
| Clubs2: | Lazio |
| Caps2: | 91 |
| Goals2: | 2 |
| Years3: | 1962 - 1964 |
| Clubs3: | Pescara |
| Caps3: | 40 |
| Goals3: | 0 |
Nicola Lo Buono (born 4 June 1933 in Bari, Italy) was an Italian football defender.