| Type: | Bishop |
| Honorific-Prefix: | Most Reverend |
| Nicolò Leti | |
| Bishop of Acquapendente | |
| Church: | Catholic Church |
| Diocese: | Diocese of Acquapendente |
| Term: | 1655–1674 |
| Predecessor: | Pompeo Mignucci |
| Successor: | Lodovico Magni |
| Birth Date: | 1605 |
| Birth Place: | Spoleto, Italy |
Nicolò Leti was a Roman Catholic prelate who served as Bishop of Acquapendente (1655–1674).
Nicolò Leti was born in Spoleto, Italy in 1605.On 14 June 1655, he was appointed during the papacy of Pope Alexander VII as Bishop of Acquapendente.He served as Bishop of Acquapendente until his resignation on 30 September 1674.