| Honorific-Prefix: | Most Reverend |
| Nicolás de Ramos y Santos | |
| Archbishop of Santo Domingo | |
| Church: | Catholic Church |
| Diocese: | Archdiocese of Santo Domingo |
| Term: | 1592–1599 |
| Predecessor: | Alfonso López de Avila |
| Successor: | Agustín Dávila Padilla |
| Birth Date: | 1531 |
| Birth Place: | Villasabariego, Spain |
| Death Date: | December 1, 1599 |
| Death Place: | Santo Domingo |
| Previous Post: | Bishop of Puerto Rico (1588 - 1592) |
| Nationality: | Spanish |
Nicolás de Ramos y Santos (1531 - December 1, 1599) was a Roman Catholic prelate who served as the Archbishop of Santo Domingo (1592 - 1599) and the third Bishop of Puerto Rico (1588 - 1592).[1] [2]
Nicolás de Ramos y Santos was born in Villasabariego, Spain and ordained a priest in the Order of Friars Minor. On February 12, 1588, he was appointed by the King of Spain and confirmed by Pope Sixtus V as Bishop of Puerto Rico. On July 13, 1592, he was appointed by the King of Spain and confirmed by Pope Clement VIII as Archbishop of Santo Domingo where served until his death on December 1, 1599.