Nicki Packer Explained

Nicki Packer (also known as Nicolle Packer) FRSC is an Australian college professor and researcher. She currently serves as a distinguished professor of glycoproteomics in the School of Natural Sciences at Macquarie University and principal research leader at Griffith University's Institute for Glycomics. Packer is a Fellow of the Royal Society of Chemistry and in 2021 received the Distinguished Achievement in Proteomic Sciences Award from the Human Proteome Organization. Her research focuses on biological functional of glycoconjugates by linking glycomics with proteomics and bioinformatics.

Career

Packer's research focuses on glycoconjugates, a topic at the intersection of chemistry and biological sciences which aims to identify and study the function of the collection of glycoproteins, glycolipids and proteoglycans in cells and on cell surfaces. Her research program examines the structure, function and role of glycans in cancer and microbial infections, as well as their application in therapeutics.[1]

Packer started her research career with a PhD from the University of Sydney in 1978.[2] In 1999 she co-founded Proteome Systems Limited, an Australian biotech company which developed glycoanalytical technology and informatics tools. Packer became a professor at Macquarie University in 2007 and in 2017 became a distinguished professor and also became the principal research leader at the Institute for Glycomics at Griffith University.

Packer is academic lead of the Australian Proteome Analysis Facility at Macquarie University.[3] In 2017 Packer co-founded the Human Glycoproteomics Initiative (HGI) as part of the Human Proteome Organisation (HUPO)[4] and the Australian Glycoscience Society Glyco@Oz in 2019 to connect Australian glycoscientists.[5] She was deputy director of Macquarie University's Biomolecular Discovery Research Centre.[6]

Packer has had multiple roles in ARC-funded research centres, including:

Awards and prizes

Packer's awards and prizes include:

Media

Packer's glycoproteomics work has been reported in The Toronto Star,[18] The Age,[19] BioSpectrum Asia[20] and by the Royal Society of Chemistry.[21] Her work with The Australian biotechnology company Proteome Systems was reported in the New York Times.[22] Packer's work on the role of sugars in a wide range of human diseases was featured in the Macquarie University publication, The Lighthouse.[23]

Publications

Packer has published over 250 journal articles and book chapters, has over 12,000 citations and has an h-index of 61 (as at April 2022).[24] Packer is an editor of the textbook Essentials of Glycobiology.[25]

Selected journal articles

References

  1. Web site: Nicki Packer . 2022-04-11 . Macquarie University . en.
  2. Web site: Packer . Nicolle . 1978 . Morphogenesis and lipids of the yeast Trigonopsis variabilis. . 2022-04-14 . University of Sydney.
  3. Web site: Administration . Staff Profiles . 2022-04-07 . Macquarie University . en-au.
  4. Web site: HUPO - Human Glycoproteomics Initiative . 2022-04-11 . www.hupo.org . en.
  5. Web site: 2020-01-19 . About Us . 2022-04-07 . Glyco@Oz . en.
  6. Web site: Administration . Our people . 2022-04-07 . Macquarie University . en-au.
  7. Web site: Distinguished Prof Nicolle Packer . 2022-04-07 . Faab Australia . 2 February 2022 . en-AU.
  8. Web site: About Us . 2022-04-07 . ARC Centre of Excellence in Synthetic Biology . en-AU.
  9. Web site: Prof Nicki Packer – ARC Centre for Innovations in Peptide and Protein Science . 2022-04-07 . en-AU.
  10. Web site: Our People . 2022-04-07 . CNBP . en-US.
  11. Web site: Grant - Grants Data Portal . 2022-04-11 . dataportal.arc.gov.au.
  12. Web site: APS Awards . 2022-10-09 . Australasian Proteomics Society . en-AU.
  13. Web site: HUPO - HUPO Awards - 2021 Recipients . 2022-04-07 . hupo.org.
  14. Web site: New Distinguished Professors announced This Week At Macquarie University . 2022-04-07 . en-AU.
  15. Web site: Administration . News and events . 2022-04-07 . Macquarie University . en-au.
  16. Web site: Past MCP ASBMB Award Winners . 2022-04-07 . www.glycobiology.org.
  17. Web site: A celebration of world-leading research with world-changing impact This Week At Macquarie University . 2022-04-07 . en-AU.
  18. News: 2007-04-29 . A week's worth of science news . en-CA . The Toronto Star . 2022-04-07 . 0319-0781.
  19. Web site: 2005-07-11 . Think tank . 2022-04-07 . The Age . en.
  20. Web site: Patrys' cancer diagnostic gets Australian govt grant . 2022-04-07 . www.biospectrumasia.com . en.
  21. Web site: Editor Viewpoints: Unlocking the cell's sugary secrets . 2022-04-07 . Royal Society of Chemistry . 26 June 2020 . en-GB.
  22. News: Rosenthal . Elisabeth . 2005-09-05 . Antidoping Agency Seeks Test for EPO That Is Definitive . en-US . The New York Times . 2022-04-07 . 0362-4331.
  23. Web site: Administration . 2018-03-22 . Sugar is involved in almost all human diseases, new research . 2022-04-07 . The Lighthouse . en-au.
  24. Web site: Scopus preview - Packer, Nicolle - Author details - Scopus . 2022-04-14 . www.scopus.com.
  25. Book: Essentials of Glycobiology . 2022 . Cold Spring Harbor Laboratory Press . 978-1-62182-421-3 . Varki . Ajit . 4th . Cold Spring Harbor (NY) . 35536922 . Cummings . Richard D. . Esko . Jeffrey D. . Stanley . Pamela . Hart . Gerald W. . Aebi . Markus . Mohnen . Debra . Kinoshita . Taroh . Packer . Nicolle H.. Varki . A. . Cummings . R. D. . Esko . J. D. . Stanley . P. . Hart . G. W. . Aebi . M. . Mohnen . D. . Kinoshita . T. . Packer . N. H. . Prestegard . J. H. . Schnaar . R. L. . Seeberger . P. H. . 10.1101/9781621824213 . 1 November 2024 .
  26. Oliveira . Tiago . Thaysen-Andersen . Morten . Packer . Nicolle H. . Kolarich . Daniel . 2021-08-27 . The Hitchhiker's guide to glycoproteomics . Biochemical Society Transactions . en . 49 . 4 . 1643–1662 . 10.1042/BST20200879 . 0300-5127 . 8421054 . 34282822.
  27. Varki . Ajit . Cummings . Richard D . Aebi . Markus . Packer . Nicole H . Seeberger . Peter H . Esko . Jeffrey D . Stanley . Pamela . Hart . Gerald . Darvill . Alan . Kinoshita . Taroh . Prestegard . James J . December 2015 . Symbol Nomenclature for Graphical Representations of Glycans . Glycobiology . en . 25 . 12 . 1323–1324 . 10.1093/glycob/cwv091 . 0959-6658 . 4643639 . 26543186.
  28. Jensen . Pia H . Karlsson . Niclas G . Kolarich . Daniel . Packer . Nicolle H . July 2012 . Structural analysis of N- and O-glycans released from glycoproteins . Nature Protocols . en . 7 . 7 . 1299–1310 . 10.1038/nprot.2012.063 . 22678433 . 20516889 . 1754-2189.
  29. Cooper . Catherine A. . Gasteiger . Elisabeth . Packer . Nicolle H. . February 2001 . GlycoMod - A software tool for determining glycosylation compositions from mass spectrometric data . Proteomics . 1 . 2 . 340–349 . 10.1002/1615-9861(200102)1:2<340::aid-prot340>3.0.co;2-b . 11680880 . 8712883 . 1615-9853.
  30. Thaysen-Andersen . Morten . Kolarich . Daniel . Packer . Nicolle H. . 2021 . Glycomics & Glycoproteomics: From Analytics to Function . Molecular Omics . en . 17 . 1 . 8–10 . 10.1039/D0MO90019B . 33295916 . 228078995 . 2515-4184. free . 10072/400201 . free .
  31. York . William S . Mazumder . Raja . Ranzinger . Rene . Edwards . Nathan . Kahsay . Robel . Aoki-Kinoshita . Kiyoko F . Campbell . Matthew P . Cummings . Richard D . Feizi . Ten . Martin . Maria . Natale . Darren A . 2020-01-28 . GlyGen: Computational and Informatics Resources for Glycoscience . Glycobiology . en . 30 . 2 . 72–73 . 10.1093/glycob/cwz080 . 1460-2423 . 7335483 . 31616925.

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