| Nick Mandziuk | |
| Birth Date: | 1902 12, df=yes |
| Birth Place: | Ukraine |
| Office: | MP for Marquette |
| Term Start: | 1957 |
| Term End: | 1968 |
| Predecessor: | Stuart Garson |
| Successor: | Craig Stewart |
| Occupation: | lawyer |
J. Nicholas Mandziuk (13 December 1902 - 7 September 1969) was a Canadian politician in Manitoba. He represented the electoral district of Marquette in the House of Commons of Canada from 1957 to 1968.
He was a member of the Progressive Conservative Party.