| Noc: | NCA |
| Nocname: | Comité Olímpico Nicaragüense |
| Games: | Summer Olympics |
| Year: | 2012 |
| Location: | London |
| Competitors: | 6 |
| Sports: | 4 |
| Flagbearer: | Osmar Bravo |
| Gold: | 0 |
| Silver: | 0 |
| Bronze: | 0 |
| Appearances: | auto |
Nicaragua competed at the 2012 Summer Olympics in London, United Kingdom, held from 27 July to 12 August 2012. This was the nation's twelfth appearance at the Olympics, except the 1988 Summer Olympics in Seoul because of its partial support to the North Korean boycott.
Comité Olímpico Nicaragüense sent a total of 6 athletes to the Games, an equal share between men and women, to compete in 4 different sports, tying its record for the number of athletes with Beijing at a single Olympics. Among these athletes, swimmers Omar Núñez and Dalia Torrez Zamora made their second consecutive appearance. Light heavyweight boxer Osmar Bravo, on the other hand, was the nation's flag bearer at the opening ceremony. Nicaragua, however, has yet to win its first ever Olympic medal.
See main article: Athletics at the 2012 Summer Olympics. Nicaragua has selected 2 athletes by a wildcard.
See main article: Boxing at the 2012 Summer Olympics. Nicaragua has earned one quota in boxing.* [1]
See main article: Swimming at the 2012 Summer Olympics.
See main article: Weightlifting at the 2012 Summer Olympics.