Nexeridine Explained

Nexeridine[1] (INN), or as nexeridine hydrochloride (USAN) (code name Compound 673-082), is an opioid analgesic with a similar structure to those of pethidine and tramadol.[2] [3] [4] It was synthesized and assayed in 1975 but was never marketed. The active isomer is (1R,2S)-1-[(2R)-1-(Dimethylamino)-2-propanyl]-2-phenylcyclohexyl acetate hydrochloride (1:1).[5]

Notes and References

  1. US . 3974157 . 1-(Amino-alkyl)-2-aryl-cyclohexane alcohols and esters .
  2. Book: Ganellin CR, Triggle DJ . Dictionary of Pharmacological Agents. 21 November 1996. CRC Press. 978-0-412-46630-4. 1417–.
  3. Book: Kar A . Medicinal Chemistry. 1 January 2005. New Age International. 978-81-224-1565-0. 268–269.
  4. Book: Unlisted Drugs, Volumes 27-28. 1975. Pharmaceutical Section, Special Libraries Association..
  5. Web site: (1R,2S)-1-[(2R)-1-(Dimethylamino)-2-propanyl]-2-phenylcyclohexyl acetate hydrochloride (1:1) ]. ChemSpider .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nexeridine".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.