| State: | NM |
| Type: | SR |
| Route: | 451 |
| Map Custom: | yes |
| Length Mi: | 3.086 |
| Length Ref: | [1] |
| Direction A: | Southern |
| Terminus A: | near Anton Chico |
| Direction B: | Northern |
| Terminus B: | near Dilia |
| Counties: | Guadalupe, San Miguel |
| Previous Type: | NM |
| Previous Route: | 450 |
| Next Type: | NM |
| Next Route: | 453 |
State Road 451 (NM 451) is a 3.1adj=midNaNadj=mid state highway in the US state of New Mexico. NM 451's northern terminus is at U.S. Route 84 (US 84) north of Dilia, and the southern terminus is at NM 119 east of Anton Chico.