| State: | NM |
| Type: | SR |
| Route: | 101 |
| Map Custom: | yes |
| Map Notes: | NM-101 highlighted in red |
| Maint: | NMDOT |
| Alternate Name: | West University Avenue |
| Length Mi: | 1.420 |
| Length Round: | 3 |
| Length Ref: | [1] |
| Established: | 1940 |
| Direction A: | West |
| Terminus A: | in Mesilla |
| Direction B: | East |
| Terminus B: | in Las Cruces |
| Counties: | Doña Ana |
| Previous Type: | NM |
| Previous Route: | 100 |
| Next Type: | NM |
| Next Route: | 102 |
State Road 101 (NM 101) is a 1.42adj=midNaNadj=mid paved, two-lane state highway in Doña Ana County in the U.S. state of New Mexico. NM 101's western terminus is at the road's junction with NM 28 within Mesilla community. The road's eastern terminus is in Las Cruces at the road's junction with NM 478. NM 101 is also known as West University Avenue.
The highway begins at the junction with NM 28 east of historic Mesilla. The road heads northeast through residential areas of Mesilla, and pecan orchards and fields of Mesilla Valley. After approximately 0.5miles the road passes by Zia Middle School. Continuing northeast 0.7miles farther, the highway runs by Fabian Garcia Botanical Gardens, part of the NMSU Agricultural Experiment Station. At this point, the highway broadens to 4 lanes before reaching its northeastern terminus at intersection with NM 478. The road continues as East University Avenue past the junction.
The original Route 101 ran from Pojoaque west to San Idelfonso as an "unimproved" road. This route became Route 4 by the 1930 map and continued with that designation through the 1931, 1934, 1935 maps. This road is presently NM 4.
NM 101 first appears on 1940 roadmap, as a connector between State College (future NMSU) and US 80/US 85 south of Las Cruces. The road construction was probably related to the New Mexico State College introducing Air Mechanics Courses starting at some point prior to 1941. The Air Mechanics Building & the Hangar Lake Building both were erected in 1941 (according to plaques on the buildings), and State College Airport was constructed around the same time. In 1960s the road was extended further east to I-25. In 1988, the New Mexico Department of Transportation (NMDOT) went through a radical road renumbering program, and NM 101 was extended further west to NM 28. In 2001 a portion of this highway between South Main Street and Telshor Boulevard was transferred to the city of Las Cruces shortening NM 101 to its current length.[2]