| State: | NH |
| Type: | NH |
| Route: | 122 |
| Map Custom: | yes |
| Map Notes: | Map of Hillsborough County in southern New Hampshire with NH 122 highlighted in red |
| Length Mi: | 12.614 |
| Direction A: | South |
| Terminus A: | Massachusetts state line in Hollis |
| Direction B: | North |
| Terminus B: | in Amherst |
| Counties: | Hillsborough |
| Previous Type: | NH |
| Previous Route: | 121A |
| Next Type: | NH |
| Next Route: | 123 |
New Hampshire Route 122 (abbreviated NH 122) is a 12.614adj=midNaNadj=mid north–south highway in Hillsborough County in southeastern New Hampshire, United States. The highway runs from Amherst south to Hollis on the Massachusetts border.
The southern terminus of NH 122 is at the Massachusetts state line in Hollis, where the road continues into Massachusetts as an unnumbered local road in the town of Pepperell. The northern terminus of NH 122 is at an interchange with New Hampshire Route 101 in Amherst.