| Province: | NB |
| Type: | NB |
| Route: | 335 |
| Maint: | New Brunswick Department of Transportation |
| Length Km: | 13.47 |
| Length Ref: | [1] |
| Length Round: | 1 |
| Direction A: | North |
| Direction B: | South |
| Terminus A: | in Caraquet |
| Cities: | Caraquet, Saint-Simon |
| Terminus B: | in Evangeline |
| Previous Type: | NB |
| Previous Route: | 330 |
| Next Type: | NB |
| Next Route: | 340 |
Route 335 or Saint-Simon Road is a 13km (08miles) long, north–south secondary highway in the southeastern portion of New Brunswick, Canada.
The route's northern terminus in the community of Caraquet. The road travels south crossing the Saint-Simon River to the community of Saint-Simon. From there, the road crosses the Brideau River and ends in Evangeline without any other intersecting routes.