| Province: | NB |
| Type: | NB |
| Route: | 165 |
| Maint: | New Brunswick Department of Transportation |
| Length Km: | 22.06 |
| Length Ref: | [1] |
| Length Round: | 1 |
| Established: | 2003 |
| Direction A: | North |
| Direction B: | South |
| Terminus A: | in Woodstock |
| Cities: | Woodstock, Lakeland Ridges |
| Terminus B: | in Lakeland Ridges |
| Previous Type: | NB |
| Previous Route: | 161 |
| Next Type: | NB |
| Next Route: | 170 |
Route 165 is a 22km (14miles)-long north–south secondary highway in the western New Brunswick, Canada.
The route's northern terminus is in downtown Woodstock, New Brunswick at Route 103, where the road is known as Main Street. From there, it runs south along the western bank of the Saint John River to the small village of Lakeland Ridges. From there, the highway stops following the Saint John River and takes a slight southern turn which brings it to its terminus at an intersection with Route 2 (exit 212) and Route 122.
Route 165 was created in 2003 upon the opening of a new twinned stretch of Route 2 (the Trans-Canada Highway). It consists of an "orphaned" section of Route 2 between Lakeland Ridges and Bulls Creek, with connections along a former stretch of Route 103 from Bulls Creek to Woodstock and a small section of former Route 122 in Lakeland Ridges.