Neutrophilic dermatosis of the dorsal hands explained
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| Synonym: | Pustular vasculitis of the dorsal hands |
| Specialty: | Dermatology |
Neutrophilic dermatosis of the dorsal hands (NDDH) is a skin condition that presents with edematous pustular or ulcerative nodules or plaques localized to the dorsal hands.[1] [2]
Signs and symptoms
Neutrophilic dermatosis of the dorsal hands is characterized by bullae, pustules, and delicate erythematous plaques on the hands' dorsa.[3]
Causes
Neutrophilic dermatosis of the dorsal hands is often associated with other conditions. Hematological disorders such as myelodysplastic syndrome and plasma cell dyscrasias are common.[3]
Diagnosis
The histopathology of NDDH lesions shows a dense neutrophil infiltrate in the dermis, which is typically linked to leukocytoclastic debris and subepidermal edema.[4]
Treatment
Systemic corticosteroids are the main method of treatment.[3]
See also
Further reading
- DEL POZO . Jesús . SACRISTÁN . Felipe . MARTÍNEZ . Walter . PARADELA . Sabela . FERNÁNDEZ-JORGE . Beatriz . FONSECA . Eduardo . Neutrophilic dermatosis of the hands: Presentation of eight cases and review of the literature . The Journal of Dermatology . Wiley . 34 . 4 . March 9, 2007 . 0385-2407 . 10.1111/j.1346-8138.2007.00261.x . 243–247 . 17352721 . 34488900 . none.
- Galaria . Noreen A. . Junkins-Hopkins . Jacqueline M. . Kligman . Douglas . James . William D. . Neutrophilic dermatosis of the dorsal hands: Pustular vasculitis revisited . Journal of the American Academy of Dermatology . Elsevier BV . 43 . 5 . 2000 . 0190-9622 . 10.1067/mjd.2000.109286 . 870–874 . 11050599 . none.
Notes and References
- James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. .
- 10.1001/archderm.138.3.361. Neutrophilic Dermatosis (Pustular Vasculitis) of the Dorsal Hands. Archives of Dermatology. 138. 3. 2002. Dicaudo. David J.. Connolly. Suzanne M.. 361–365. free. 11902987.
- Micallef . Daniel . Bonnici . Maria . Pisani . David . Boffa . Michael J. . Neutrophilic dermatosis of the dorsal hands: A review of 123 cases . Journal of the American Academy of Dermatology . Elsevier BV . 88 . 6 . 2023 . 0190-9622 . 10.1016/j.jaad.2019.08.070 . 1338–1344. 31499154 . 202412220 .
- Kaur . S . Gupta . D . Garg . B . Sood . N . Neutrophilic dermatosis of dorsal hands . Indian Dermatology Online Journal . Medknow . 6 . 1 . 2015 . 42–45 . 2229-5178 . 10.4103/2229-5178.148940 . free . 25657918 . 4314889 .
