Neuropeptide FF receptor 2 explained

Neuropeptide FF receptor 2, also known as NPFF2 is a human protein encoded by the NPFFR2 gene.^[1]

See also

• Neuropeptide FF receptor

Further reading

• Cikos S, Gregor P, Koppel J . Sequence and tissue distribution of a novel G-protein-coupled receptor expressed prominently in human placenta. . Biochem. Biophys. Res. Commun. . 256 . 2 . 352–6 . 1999 . 10079187 . 10.1006/bbrc.1999.0332 .
• Parker RM, Copeland NG, Eyre HJ, etal . Molecular cloning and characterisation of GPR74 a novel G-protein coupled receptor closest related to the Y-receptor family. . Brain Res. Mol. Brain Res. . 77 . 2 . 199–208 . 2000 . 10837915 . 10.1016/S0169-328X(00)00052-8 .
• Elshourbagy NA, Ames RS, Fitzgerald LR, etal . Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. . J. Biol. Chem. . 275 . 34 . 25965–71 . 2000 . 10851242 . 10.1074/jbc.M004515200 . free .
• Bonini JA, Jones KA, Adham N, etal . Identification and characterization of two G protein-coupled receptors for neuropeptide FF. . J. Biol. Chem. . 275 . 50 . 39324–31 . 2001 . 11024015 . 10.1074/jbc.M004385200 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Laemmle B, Schindler M, Beilmann M, etal . Characterization of the NPGP receptor and identification of a novel short mRNA isoform in human hypothalamus. . Regul. Pept. . 111 . 1–3 . 21–9 . 2003 . 12609745 . 10.1016/S0167-0115(02)00220-3 . 24049458 .
• Engström M, Wurster S, Savola JM, Panula P . Functional properties of Pfr(Tic)amide and BIBP3226 at human neuropeptide FF2 receptors . Peptides . 24 . 12 . 1947–54 . 2004 . 15127947 . 10.1016/j.peptides.2003.10.009 . 3833336 .
• Mollereau C, Mazarguil H, Zajac JM, Roumy M . Neuropeptide FF (NPFF) analogs functionally antagonize opioid activities in NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells . Mol. Pharmacol. . 67 . 3 . 965–75 . 2005 . 15608144 . 10.1124/mol.104.004614 . 9919973 .
• Ankö ML, Panula P . Regulation of endogenous human NPFF2 receptor by neuropeptide FF in SK-N-MC neuroblastoma cell line . J. Neurochem. . 96 . 2 . 573–84 . 2006 . 16336216 . 10.1111/j.1471-4159.2005.03581.x . 26460239 . free .
• Ankö ML, Ostergård M, Lintunen M, Panula P . Alternative splicing of human and mouse NPFF2 receptor genes: Implications to receptor expression . FEBS Lett. . 580 . 30 . 6955–60 . 2007 . 17157836 . 10.1016/j.febslet.2006.11.063 . 29801987 . free .
• Dahlman I, Dicker A, Jiao H, etal . A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis . Am. J. Hum. Genet. . 80 . 6 . 1115–24 . 2007 . 17503329 . 10.1086/518445 . 1867099 .

External links

• Web site: Neuropeptide FF Receptors: NPFF2 . IUPHAR Database of Receptors and Ion Channels . International Union of Basic and Clinical Pharmacology . 2008-12-09 . 2016-03-03 . https://web.archive.org/web/20160303181607/http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=3001 . dead .

Notes and References

1. Web site: Entrez Gene: NPFFR2 neuropeptide FF receptor 2.