| Image Coa: | Nesse-Apfelstädt coa.svg |
| Image Plan: | Nesse-Apfelstädt_in_GTH.svg |
| State: | Thüringen |
| District: | Gotha |
| Divisions: | 6 villages |
| Elevation: | 265 |
| Area: | 39.47 |
| Postal Code: | 99192 |
| Area Code: | 036202, 036208 |
| Licence: | GTH |
| Gemeindeschlüssel: | 16067087 |
| Website: | nesse-apfelstaedt.de |
| Mayor: | Christian Jacob[1] |
| Leader Term: | 2022 - 28 |
| Year: | 2009 |
| Coordinates: | 50.9167°N 65°W |
Nesse-Apfelstädt is a municipality in the district of Gotha, in Thuringia, Germany. It was formed by the merger of the previously independent municipalities Apfelstädt, Gamstädt, Ingersleben and Neudietendorf, on 1 December 2009.