Neridronic acid explained

Neridronic acid (INN; the anion is called neridronate) is a bisphosphonate. In Italy it is used to treat Osteogenesis imperfecta and Paget's disease of bone.[1]

A 2013 clinical trial suggests CRPS Type I (Complex regional pain syndrome) responds to treatment with intravenous neridronate.[2]

Notes and References

  1. 19761412 . 10.1517/17425250903029190 . 5 . Neridronic acid for the treatment of bone metabolic diseases . Expert Opin Drug Metab Toxicol . 1305–11 . Gatti D, Viapiana O, Idolazzi L, Fracassi E, Adami S. 2009 . 10 . 22274296 .
  2. Varenna M, Adami S, Rossini M, etal . Treatment of complex regional pain syndrome type I with neridronate: a randomized, double-blind, placebo-controlled study . Rheumatology . 52 . 3 . 534–42 . March 2013 . 23204550 . 10.1093/rheumatology/kes312. free .

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