Nepenthes misoolensis is a tropical pitcher plant endemic to Misool Island, in the Rajah Ampat Archipelago, in Southwest Papua, Indonesia.
The species is known to occur in Misool Island. The species was found in a karst, at an elevation range of 2 to 4 meters above sea level.
The species is named from the contraction of "Misool", the type locality, and the Latin ending "-ensis" which means "from", meaning "from Misool", within which the species is apparently endemic.