Neisseria sigma-E sRNA explained

Neisseria sigma-E sRNA
Width:	276px
Symbol:	NSE_sRNA
Rfam:	RF02270
Rna Type:	Gene
Tax Domain:	Bacteria

Neisseria sigma-E sRNA (NSE sRNA) is a non-coding RNA found in the bacterial genus Neisseria, including the two pathogens N. meningitidis and N. gonorrhoeae. The RNA was discovered in a screen for genes differentiated by high expression of the Sigma factor, sigma E.^[1] Seven genes were predicted to be regulated by NSE sRNA, including fur, nadC and a putative TetR family transcriptional regulator, through base-pairing interactions with the 5' UTR. The sRNA transcript is terminated by a rho independent terminator.

See also:

• NrrF sRNA
• Neisseria RNA thermometers
• Neisseria sibling sRNAs NmsR/RcoF

Notes and References

1. Huis in 't Veld RA, Willemsen AM, van Kampen AH, Bradley EJ, Baas F, Pannekoek Y, van der Ende A . Deep sequencing whole transcriptome exploration of the σE regulon in Neisseria meningitidis . PLOS ONE . 6 . 12 . e29002 . 2011 . 22194974 . 3240639 . 10.1371/journal.pone.0029002 . Yang . Pan-Chyr . free . 2011PLoSO...629002H .